The study of how a drug moves through the body — absorption, distribution, metabolism, and excretion (ADME).
"Pharmacokinetics" is filed under Pharmacology in the PeptideAtlas glossary, alongside 29 other terms in that group.
The term applies directly to 2 compound profiles here: Tesamorelin (evidence A), Danuglipron (evidence B). Each profile states the strength of the human evidence rather than only what the compound is claimed to do.
1 other glossary entry refer to this term in their own definition, which is usually the fastest way to see how it is used in practice.
The study of what a drug does to the body — its mechanism of action, therapeutic effects, and dose-response relationships. Complementary to pharmacokinetics.
The proportion of a substance that enters the circulation when introduced into the body and is able to have an active effect. Different administration routes affect bioavailability.
The time required for the concentration of a substance in the body to decrease by half. Determines dosing frequency and accumulation patterns.
Compounds where this applies: Tesamorelin, Danuglipron.
Terms that reference this one: Pharmacodynamics.
More Pharmacology terms: Bioavailability, Half-Life, Pharmacodynamics, First-Pass Metabolism, Receptor Agonist, Receptor Antagonist, Desensitization, Tachyphylaxis, Downregulation, GLP-1 (Glucagon-Like Peptide-1), GIP (Glucose-Dependent Insulinotropic Polypeptide), Glucagon, Amylin, Ghrelin, Growth Hormone Secretagogue (GHS), GHRP (Growth Hormone Releasing Peptide), GHRH (Growth Hormone Releasing Hormone), GHS-R1a (Growth Hormone Secretagogue Receptor), Secretagogue, Melanocortin Receptor.