A peptide hormone co-secreted with insulin by pancreatic beta cells. It slows gastric emptying, suppresses glucagon secretion, and promotes satiety. Pramlintide is a synthetic amylin analogue; cagrilintide is a long-acting acylated amylin analogue used for weight management.
"Amylin" is filed under Pharmacology in the PeptideAtlas glossary, alongside 29 other terms in that group.
The term applies directly to 6 compound profiles here: Cagrilintide (evidence B), Pramlintide (evidence A), Amylin (evidence B), Eloralintide (evidence C), CAGRILINTIDE + SEMAGLUTIDE (evidence D), Amycretin (evidence C). Each profile states the strength of the human evidence rather than only what the compound is claimed to do.
The proportion of a substance that enters the circulation when introduced into the body and is able to have an active effect. Different administration routes affect bioavailability.
The time required for the concentration of a substance in the body to decrease by half. Determines dosing frequency and accumulation patterns.
The study of how a drug moves through the body — absorption, distribution, metabolism, and excretion (ADME).
Compounds where this applies: Cagrilintide, Pramlintide, Amylin, Eloralintide, CAGRILINTIDE + SEMAGLUTIDE, Amycretin.
More Pharmacology terms: Bioavailability, Half-Life, Pharmacokinetics, Pharmacodynamics, First-Pass Metabolism, Receptor Agonist, Receptor Antagonist, Desensitization, Tachyphylaxis, Downregulation, GLP-1 (Glucagon-Like Peptide-1), GIP (Glucose-Dependent Insulinotropic Polypeptide), Glucagon, Ghrelin, Growth Hormone Secretagogue (GHS), GHRP (Growth Hormone Releasing Peptide), GHRH (Growth Hormone Releasing Hormone), GHS-R1a (Growth Hormone Secretagogue Receptor), Secretagogue, Melanocortin Receptor.