A class of synthetic peptides that stimulate growth hormone release by activating the ghrelin receptor (GHS-R1a). Includes GHRP-2, GHRP-6, hexarelin, and ipamorelin. Each variant has different potency and side-effect profiles regarding hunger, cortisol, and prolactin.
"GHRP (Growth Hormone Releasing Peptide)" is filed under Pharmacology in the PeptideAtlas glossary, alongside 29 other terms in that group.
The proportion of a substance that enters the circulation when introduced into the body and is able to have an active effect. Different administration routes affect bioavailability.
The time required for the concentration of a substance in the body to decrease by half. Determines dosing frequency and accumulation patterns.
The study of how a drug moves through the body — absorption, distribution, metabolism, and excretion (ADME).
More Pharmacology terms: Bioavailability, Half-Life, Pharmacokinetics, Pharmacodynamics, First-Pass Metabolism, Receptor Agonist, Receptor Antagonist, Desensitization, Tachyphylaxis, Downregulation, GLP-1 (Glucagon-Like Peptide-1), GIP (Glucose-Dependent Insulinotropic Polypeptide), Glucagon, Amylin, Ghrelin, Growth Hormone Secretagogue (GHS), GHRH (Growth Hormone Releasing Hormone), GHS-R1a (Growth Hormone Secretagogue Receptor), Secretagogue, Melanocortin Receptor.