The specific order of amino acids in a peptide chain, typically written using three-letter or one-letter amino acid codes. Determines the peptide's structure and function.
"Sequence" is filed under Basics in the PeptideAtlas glossary, alongside 12 other terms in that group.
The term applies directly to 22 compound profiles here: Ipamorelin (evidence D), Dulaglutide (evidence A), Albiglutide (evidence A), Matrixyl (evidence F), Palmitoyl Tripeptide-1 (evidence F), Palmitoyl Tripeptide-5 (evidence F), Sh-Polypeptide-1 (evidence F), Pinealon (evidence D), and others. Each profile states the strength of the human evidence rather than only what the compound is claimed to do.
3 other glossary entries refer to this term in their own definition, which is usually the fastest way to see how it is used in practice.
The building blocks of peptides and proteins. There are 20 standard amino acids that combine in various sequences to form peptides.
A peptide design strategy where the amino acid sequence is reversed and D-amino acids replace L-amino acids. This preserves side-chain topology while dramatically increasing resistance to enzymatic degradation. FOXO4-DRI uses this approach.
An FDA product recall classification indicating a situation where use of or exposure to the product may cause temporary or medically reversible adverse health consequences. All peptide-related FDA recalls to date have been Class II.
A short chain of amino acids (typically 2-50 amino acids) linked by peptide bonds. Shorter than proteins but with diverse biological activities.
Compounds where this applies: Ipamorelin, Dulaglutide, Albiglutide, Matrixyl, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Sh-Polypeptide-1, Pinealon, Cortagen, Bremelanotide, Romiplostim, Icatibant, Eptifibatide, Bivalirudin, PNC-27, SLU-PP-332, Thymalin, Vilon, Livagen, Cardiogen.
Terms that reference this one: Amino Acid, D-Retro-Inverso, Class II Recall.
More Basics terms: Amino Acid, Peptide, Peptide Bond, Analogue, Bioregulator, Neuropeptide, Signaling Peptide, D-Retro-Inverso, Cyclization, PEGylation, Acylation, DAC (Drug Affinity Complex).