Vilon (Lys-Glu, KE) is a synthetic dipeptide (MW ~275.3 g/mol) developed by Khavinson as a simplified synthetic version of the active component in thymalin. It is one of the shortest bioregulatory peptides proposed to have immunomodulatory activity. According to Khavinson bioregulation theory, this dipeptide interacts with specific DNA sequences to modulate gene expression related to immune function and thymopoiesis. Published primarily in Russian literature with limited Western validation.
Category: Immune / Anti-Aging. Evidence rating: D (animal/preclinical only).
Clinical status: Published in Russian biogerontology literature. Limited peer review in English-language journals.
Vilon (Lys-Glu) is proposed to complement DNA sequences in gene promoter regions controlling immune-related genes, modulating their transcription. Specifically, it has been reported to increase chromatin accessibility at immune gene loci, enhance T-cell proliferation and differentiation, restore…
Safety considerations: Reported as well-tolerated in Russian clinical use; No serious adverse events in published literature; As a simple dipeptide, low immunogenicity expected.
Reviewed by the PeptideAtlas Editorial Team.
| Amino-acid sequence | Lys-Glu (KE) |
|---|---|
| Molecular formula | C11H21N3O5 |
| Molecular weight | ~275.3 g/mol |
| Half-life | ~15-30 minutes (dipeptide, rapid degradation) |
| Production method | synthetic |
| Anti-doping status | not-listed |
| US regulatory status | Research peptide. Not FDA-approved. |
Related peptides: Thymalin.
Vilon (Lys-Glu) is a synthetic dipeptide proposed to be one of the active immunomodulatory sequences within the complex thymalin extract. It represents Khavinson attempt to identify the minimal active peptide responsible for thymalin immune effects.
Vilon is a synthetic dipeptide bioregulator researched for its potential effects on thymus function and immune aging.
VILON has been studied for: Thymus support, Immune aging, Longevity research. Thymus peptide; dipeptide bioregulator.
Short peptide that may influence thymic gene expression and immune cell development.