Myristoyl pentapeptide-17 is a lipopeptide used in eyelash and eyebrow growth cosmetic products. It is proposed to promote hair growth by stimulating keratin gene expression in hair follicle cells. The myristoyl (C14 fatty acid) chain enhances follicular penetration. Clinical evidence is very limited, consisting primarily of manufacturer-conducted studies on eyelash growth.
Category: Cosmetic Peptide. Evidence rating: F (anecdotal/unsupported).
Clinical status: Cosmetic ingredient. Very limited published clinical data.
Myristoyl pentapeptide-17 is proposed to upregulate keratin gene expression in hair follicle keratinocytes, promoting hair shaft production and potentially increasing lash/brow thickness and length. The myristoyl chain provides lipophilicity for penetration into the hair follicle. Detailed…
Safety considerations: Generally well tolerated in lash/brow formulations; No significant adverse effects reported; Applied to sensitive eye area — formulation quality is important.
Reviewed by the PeptideAtlas Editorial Team.
| Production method | synthetic |
|---|---|
| Anti-doping status | not-listed |
| US regulatory status | Cosmetic ingredient. Not FDA-regulated as a drug. |
Related peptides: Matrixyl, Matrixyl 3000, Snap-8.
Almost certainly not. Bimatoprost (Latisse) is an FDA-approved drug with robust clinical trial data demonstrating significant lash growth. Myristoyl pentapeptide-17 is a cosmetic ingredient with very limited clinical evidence. They should not be considered equivalent.
Myristoyl pentapeptide-17 is a lipopeptide used in eyelash and eyebrow growth cosmetic products. It is proposed to promote hair growth by stimulating keratin gene expression in hair follicle cells. The myristoyl (C14 fatty acid) chain enhances follicular penetration. Clinical evidence is very limited, consisting primarily of manufacturer-conducted studies on eyelash growth.
On the PeptideAtlas A–F scale, Myristoyl Pentapeptide-17 is rated F (Safety Concern). Safety concerns, misleading claims, or no credible basis
Cosmetic ingredient. Very limited published clinical data.
Myristoyl pentapeptide-17 is proposed to upregulate keratin gene expression in hair follicle keratinocytes, promoting hair shaft production and potentially increasing lash/brow thickness and length. The myristoyl chain provides lipophilicity for penetration into the hair follicle. Detailed peer-reviewed mechanistic studies are not readily available; most mechanistic information comes from…
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