Muscle stem cells located between the sarcolemma and basement membrane of muscle fibers. They activate in response to muscle damage or mechanical stress to repair and regenerate muscle tissue. MGF (Mechano Growth Factor) is studied for its role in satellite cell activation.
"Satellite Cells" is filed under Cell Biology in the PeptideAtlas glossary, alongside 6 other terms in that group.
The term applies directly to 2 compound profiles here: PEG-MGF (evidence D), MGF (evidence D). Each profile states the strength of the human evidence rather than only what the compound is claimed to do.
A phospholipid found almost exclusively in the inner mitochondrial membrane, essential for the function of respiratory chain complexes and ATP production. Cardiolipin damage is linked to aging and metabolic disease. The peptide SS-31 (Elamipretide) selectively binds cardiolipin to stabilize mitochondrial function.
The inward folds of the inner mitochondrial membrane where the electron transport chain and ATP synthase are located. Cristae structure determines mitochondrial efficiency. Cardiolipin stabilization by SS-31 helps maintain normal cristae architecture.
A cellular recycling process where damaged proteins and organelles are engulfed and degraded. Important for cellular maintenance and longevity. Fasting, AMPK activation, and certain peptides may promote autophagy.
Compounds where this applies: PEG-MGF, MGF.
More Cell Biology terms: Cardiolipin, Cristae, Autophagy, Apoptosis, Mitochondrial Biogenesis, Blood-Brain Barrier (BBB).