N-Acetyl Semax Amidate (NASA) is a modified derivative of Semax, a synthetic analog of ACTH(4-10) developed in Russia. The N-acetyl and C-amide modifications are intended to enhance metabolic stability and membrane permeability compared to the parent Semax peptide. It is a research chemical with no published clinical trials, no regulatory approval in any jurisdiction, and no peer-reviewed human efficacy or safety data.
1 independent Janoshik purity test cover N-Acetyl Semax Amidate across 1 vendor.
Category: Nootropic / Neuroprotective. Evidence rating: D (animal/preclinical only).
Clinical status: Research chemical only. No published clinical trials. No regulatory evaluation. All pharmacological claims are extrapolated from Semax data.
The proposed mechanism is extrapolated from Semax research. Semax (Met-Glu-His-Phe-Pro-Gly-Pro) is the heptapeptide fragment ACTH(4-10) with a C-terminal Pro-Gly-Pro extension that enhances stability. N-Acetyl Semax Amidate adds N-terminal acetylation and C-terminal amidation to further resist…
Safety considerations: No safety data exist for N-Acetyl Semax Amidate specifically; Semax (parent compound) has a favorable safety profile in Russian clinical use; The additional chemical modifications introduce unknown safety variables.
Reviewed by the PeptideAtlas Editorial Team.
| Production method | synthetic |
|---|---|
| Anti-doping status | not-listed |
| US regulatory status | Not FDA-approved or evaluated. Sold as a research chemical online. No regulatory status. |
| Vendor | Best tested purity |
|---|
Related peptides: Semax, Cerebrolysin, Pinealon.
N-Acetyl Semax Amidate adds N-terminal acetylation and C-terminal amidation to the Semax sequence. These modifications theoretically enhance metabolic stability. However, no studies have confirmed whether this translates to improved efficacy, different pharmacology, or changed safety profile.
No. Zero clinical trials have been published for N-Acetyl Semax Amidate. All claimed benefits are extrapolated from Semax research. The modifications may alter the pharmacological profile in unpredictable ways.
N-Acetyl Semax Amidate is not a controlled substance in most jurisdictions, but it is also not an approved drug or supplement. It exists in a regulatory grey area as a "research chemical." Quality and safety are not guaranteed.
Vendors with independent lab tests for it: Polaris Peptides.