Bronchogen (Ala-Glu-Asp, AED) is a synthetic tripeptide (MW ~333.3 g/mol) from the Khavinson bioregulatory peptide family, designed as a lung-specific peptide for respiratory tissue regeneration. It is proposed to restore function of bronchial epithelium and improve respiratory parameters in aging or chronic lung disease. Published primarily in Russian biogerontology literature with limited Western validation.
Category: Respiratory / Anti-Aging. Evidence rating: D (animal/preclinical only).
Clinical status: Russian clinical studies in elderly patients with chronic bronchitis. Limited peer review.
Bronchogen is proposed to interact with DNA regulatory regions in bronchial epithelial cells, restoring gene expression patterns related to mucociliary clearance, epithelial barrier integrity, and surfactant production. In animal models of chronic bronchitis and aged lung tissue, it reportedly…
Safety considerations: Reported as well-tolerated in Russian clinical use; No serious adverse events in published literature; Simple tripeptide structure suggests low toxicity risk.
Reviewed by the PeptideAtlas Editorial Team.
| Amino-acid sequence | Ala-Glu-Asp (AED) |
|---|---|
| Molecular formula | C12H19N3O8 |
| Molecular weight | ~333.3 g/mol |
| Half-life | ~15-30 minutes |
| Production method | synthetic |
| Anti-doping status | not-listed |
| US regulatory status | Research peptide. Not FDA-approved. |
Related peptides: Chonluten.
Compare: Bronchogen vs Chonluten.
Bronchogen has limited evidence from Russian studies suggesting improvements in respiratory parameters in elderly patients. It has not been validated in controlled Western clinical trials. For serious lung conditions, evidence-based treatments should be prioritized.
Bronchogen is a Khavinson bioregulator tripeptide (Ala-Glu-Asp) researched for bronchial and respiratory tissue support, particularly in age-related respiratory decline.
BRONCHOGEN has been studied for: Bronchial tissue support, Respiratory function, Mucosal health, Age-related lung support. Khavinson bioregulator; respiratory/bronchial tissue focus.
Short bioregulator peptide that interacts with DNA promoter regions in bronchial epithelial cells, potentially modulating gene expression related to mucosal defense and tissue repair.
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