High-Purity Nucleic Acid Amidites and Amino Acid Building Blocks

Research platforms supply high-quality building blocks for nucleic acids, peptides, and conjugates from discovery to commercial stages. These include extensive catalogs of amidites, nucleotides, and modified amino acids with purity levels exceeding 99%. Specific products feature detailed molecular…

Essential Building Blocks for Nucleic Acids and Peptides

Contract research and development manufacturing organizations provide solutions for nucleic acids, peptides, and synthetic conjugates. These offerings include building blocks suitable for stages from discovery to commercialization. Such products enable faster and more cost-effective development.

Catalogs cover nucleotides, amino acids, amidites, and custom builders. Researchers access categories like ASO amidites, RNA amidites, PMO monomers, and siRNA amidites. Additional series include specialty DNA amidites, base modifications, and skeletal modifications.

Nucleic Acid Product Categories

Nucleic acid catalogs support progression from discovery to development and commercial manufacturing. Key categories consist of Adenine Series, Thymine Series, Cytosine Series, Guanine Series, Uracil Series, and Inosine Series. Other groups feature Abasic Series, Reverse Amidite, α-DNA Series, L-DNA Amidite, and L-RNA Amidite.

Further modifications include 2'-amidite Series, 2'-OMe Series, 2'-F Series, 2'-MOE Series, 2'-OH Series, 2'-amino Series, 2'-aminoethyl Series, and 2'-NMA Series. Advanced options cover LNA Series, GNA Series, TNA Series, UNA Series, ENA Series, Me-P Series, PACE Series, and OMe-P Series. Modifiers encompass Amino Modifiers, Thiol Modifiers, Phosphate Modifiers, and Spacer Modifiers.

Nucleotides and precursors include Canonical NTP, Mono- and Di-Nucleotides, Cap Precursors, 7-Methyl Guanosine Reagents, 2'-OBn Series, Base Modified dNTP, Sugar Modified NTP, Deoxynucleotide Diphosphate dNDP , and Deoxynucleotides dNTPs . For more on peptide-related terms, check the Peptide Glossary /tools/peptide-glossary .

Highlighted Amidite Products

Specific nucleic acid amidites demonstrate high purity levels. For instance, 2'-MOE A Bz amidite, catalog ID STA-AM10009, has molecular formula C50H58N7O9P, CAS 251647-53-7, and purity 99%. Similarly, 2'-MOE G iBu amidite, STA-AM10010, formula C47H60N7O10P, CAS 251647-55-9, purity 99%.

DNA T amidite, STA-AM10001, Thymine Series, C40H49N4O8P, CAS 98796-51-1, purity 99%. 2'-OMe C Ac amidite, STA-AM10015, 2'-OMe Series, C42H52N5O9P, CAS 199593-09-4, purity 99%. 2'-OMe G iBu amidite, STA-AM10017, C45H56N7O9P, CAS 150780-67-9, purity 99%.

2'-F A Bz amidite, STA-AM10023, 2'-F Series, C47H51FN7O7P, CAS 136834-22-5, purity 99%. DNA A Bz amidite, STA-AM10003, Adenine Series, C47H52N7O7P, CAS 98796-53-3, purity 99%. 2'-F C Ac amidite, STA-AM10021, C41H49FN5O8P, CAS 159414-99-0, purity 99%.

Additional Specialized Amidites

2'-F U amidite, STA-AM10019, 2'-F Series, C39H46FN4O8P, CAS 146954-75-8, purity 99%. 2'-F G iBu amidite, STA-AM10024, C44H53FN7O8P, CAS 144089-97-4, purity 99%. 2'-MOE MeC Bz amidite, STA-AM10007, 2'-MOE Series, C50H60N5O10P, CAS 163759-94-2, purity 99%.

2'-OMe A Bz amidite, STA-AM10016, 2'-OMe Series, C48H54N7O8P, CAS 110782-31-5, purity 99%. 2'-OMe U amidite, STA-AM10011, C40H49N4O9P, CAS 110764-79-9, purity 99%. 2'-MOE T amidite, STA-AM10006, C43H55N4O10P, CAS 163878-63-5, purity 99%.

DNA C Bz amidite, STA-AM10002, Cytosine Series, C46H52N5O8P, CAS 102212-98-6, purity 99%. DNA G iBu amidite, STA-AM10004, Guanine Series, C44H54N7O8P, CAS 93183-15-4, purity 99%. Explore dosing tools at the Dosage & Cycle Planner /tools/peptide-dosage-planner .

LNA and Inosine Amidites

LNA G dmf amidite, STA-AM10028, LNA Series, C44H53N8O8P, CAS 709641-79-2, purity 99%. LNA A Bz amidite, STA-AM10027, C48H52N7O8P, CAS 206055-79-0, purity 99%. 2'-OMe I amidite, STA-AM10117, Inosine Series, C41H49N6O8P, CAS 128219-85-2, purity 98%.

LNA T amidite, STA-AM10025, LNA Series, C41H49N4O9P, CAS 206055-75-6, purity 99%. LNA MeC Bz amidite, STA-AM10093, C48H54N5O9P, CAS 206055-82-5, purity 99%. 2'-MOE I amidite, STA-AM10920, Inosine Series, C43H53N6O9P, CAS No data, purity 98%.

2'-MOE A Bz amidite repeats as STA-AM10009, C50H58N7O9P, CAS 251647-53-7, purity 99%.

Amino Acid Categories and Capabilities

Amino acid catalogs span from discovery to manufacturing. Categories include Derivative of Natural AA, Side Chain Modified AA, Unusual AA, Backbone Modified AA, Unnatural AA, Alpha-alkylated, Homo-natural AA, Alkenyl AA, Azido/Alkynyl AA, and Lipidated AA.

Platforms offer scalability from discovery to commercialization with large capacity. Integrated CMC covers API process R&D, manufacturing, formulation, analytical services, dossier preparation, and clinical supplies. Comprehensive analytical platforms handle method development, validation, IPC, release testing, characterization, and stability.

New technologies support oligonucleotide synthesis via biocatalysis for gRNA and Thin Film Evaporation TFE . Peptide processes use reactor-in-series with PAT data, continuous flow chromatography, and Tangential Flow Filtration TFF /precipitation. Global quality standards apply across sites, approved by major agencies. Conjugation chemistry enables collaboration among teams. Browse our catalog /catalog for related research compounds.

Key Takeaways

These high-purity products, often 99%, provide precise tools for synthesis. Detailed specifications like molecular formulas and CAS numbers ensure reliability. Researchers benefit from comprehensive categories and advanced manufacturing support.

Related reading: Palmitoyl Tripeptide: Multi-Benefit Peptide for Skin Care, Self-Assembling Peptides: Mechanisms and Biomedical Applications, Melanotan 2 Explained: Origins, Tanning Science, and Key Benefits, How to Reconstitute Lyophilized Peptides: Step-by-Step Guide.