CSBio's 2-Hour Mini-Course on SPPS Fundamentals

CSBio offers a two-hour mini-course series on the basics of solid phase peptide synthesis. The program targets labs and universities new to peptide production, including hands-on training with peptide synthesizers. It covers amino acids, proteins, synthesis methods, resins, and lab procedures for…

CSBio Introduces SPPS Training Series

CSBio has launched a series that delivers a two-hour mini-course on the essentials of solid phase peptide synthesis. This training helps labs and universities that have not produced peptides before. The company supplies them with peptide synthesizers and conducts hands-on sessions to enable quick starts in peptide production.

The mini-course gives a broad view of peptides and their synthesis methods. It aims to equip participants with practical knowledge for peptide work.

Course Introduction and Basics

The course begins with an introduction that includes a short overview and details about the instructor. Participants learn the building blocks of peptides through sections on amino acids. These cover the nature of amino acids as key components.

Next, the program explains proteins and peptides. It defines what proteins and peptides represent in biological terms. This foundation sets the stage for synthesis techniques.

Core SPPS Methods

A major section focuses on solid phase peptide synthesis, detailing how to create a peptide. It compares solution phase and solid phase approaches to peptide production. Common activation chemistries receive attention, including DIC and HBTU for forming peptide bonds.

Resin types form the solid support in SPPS. The course reviews standard resins and their specific uses. Units employed in SPPS processes also get explained.

An example illustrates peptide creation via SPPS. Reagent preparation steps follow, showing how to ready materials for synthesis.

Synthesis Cycle and Lab Practice

The synthesis cycle in SPPS undergoes detailed discussion. This outlines the repeated steps for chain assembly.

In lab settings, the course demonstrates manual peptide synthesis. It walks through each action for hands-on work without machines.

Automated synthesis uses a peptide synthesizer in the lab. The process mirrors manual steps but relies on equipment for efficiency.

Related Research and Company Details

CSBio invites notifications for new course releases. Related content includes a comparison of microwave and conduction heating for SPPS, done with University of California, Davis. Findings appeared at the 28th American Peptide Symposium.

Another post covers synthesizing a 132-mer peptide with high purity. It stresses detail for accuracy and compound purity at any length.

A piece examines peptide therapeutics against COVID-19. It reviews global research on coronavirus origins and treatments.

CSBio operates as a leading peptide instrumentation manufacturer in Silicon Valley, California. The firm offers research scale peptide synthesizers, pilot scale peptide synthesizers, commercial scale peptide synthesizers, and DNA/RNA oligonucleotide synthesizers. Contact details are 915 Linda Vista Ave, Mountain View, CA, 94043, phone +1-650-525-6200, email [email protected].

Vendors referenced: Compound Purity.

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