The tendency for studies with positive results to be published more often than studies with negative or null results. Creates a skewed evidence base that can overestimate peptide efficacy.
"Publication Bias" is filed under Evidence & Research in the PeptideAtlas glossary, alongside 14 other terms in that group.
A study where participants are randomly assigned to receive either the treatment or a control (placebo or standard care). The gold standard for establishing causality in medical research.
The first stage of clinical testing in humans, typically involving 20-100 healthy volunteers. Tests safety, dosage, and side effects. Most peptides in the research pipeline are at or before this stage.
Clinical trials involving 100-300 patients with the target condition. Tests efficacy and further evaluates safety. Provides initial evidence of whether a peptide works for its intended purpose.
More Evidence & Research terms: Randomized Controlled Trial (RCT), Phase I Trial, Phase II Trial, Phase III Trial, Systematic Review, Meta-Analysis, In Vitro, In Vivo, Preclinical, Placebo Effect, p-Value, Biomarker, Endpoint, Observational Study.