A sugar alcohol commonly used as a bulking agent and cryoprotectant in lyophilized peptide formulations. It forms the visible powder cake in the vial and helps protect the peptide during the freeze-drying process.
"Mannitol" is filed under Preparation in the PeptideAtlas glossary, alongside 12 other terms in that group.
1 other glossary entry refer to this term in their own definition, which is usually the fastest way to see how it is used in practice.
An inactive substance that serves as a carrier or stabilizer in a formulation. Mannitol is a common excipient in lyophilized peptide products.
Sterile water containing 0.9% benzyl alcohol as a preservative. Used to reconstitute lyophilized peptides. Unlike sterile water, it inhibits bacterial growth and allows multi-dose use.
Water that has been sterilized and contains no preservatives. Unlike bacteriostatic water, it does not inhibit bacterial growth and should be used for single-dose preparations only.
The process of adding a solvent (usually bacteriostatic water) to a lyophilized peptide to create a liquid solution for use.
Terms that reference this one: Excipient.
More Preparation terms: Bacteriostatic Water, Sterile Water, Reconstitution, Lyophilization, Lyophilized, Vial, Aliquot, Diluent, Excipient, Peptide Blend, Cold Chain, Enteric Coating.