A condition or factor that makes a particular treatment or procedure inadvisable. Absolute contraindications mean the treatment should never be used; relative contraindications mean the benefits may outweigh risks in some cases.
"Contraindication" is filed under Clinical & Safety in the PeptideAtlas glossary, alongside 15 other terms in that group.
Any undesirable experience associated with the use of a medical product, whether or not considered related to the product. Serious adverse events include hospitalization, disability, or life-threatening outcomes.
The FDA's most serious warning placed on a drug's prescribing information, indicating significant risks of serious or life-threatening adverse effects. GLP-1 agonists carry a black box warning for thyroid C-cell tumors based on rodent studies.
The range of drug dosages between the minimum effective dose and the dose that produces unacceptable toxicity. Narrow therapeutic windows require careful dose monitoring.
More Clinical & Safety terms: Adverse Event, Black Box Warning, Therapeutic Window, Drug Interaction, Washout Period, Anaphylaxis, Immunogenicity, Anti-Drug Antibodies (ADA), MedWatch, REMS (Risk Evaluation and Mitigation Strategy), Gastroparesis, Pancreatitis, Gallbladder Disease, Injection Site Reaction, Sterile Abscess.