Compare Histrelin (evidence A) and Kisspeptin (evidence C) on mechanism, clinical status, safety, and dosing.
Histrelin is a synthetic GnRH agonist nonapeptide analog (MW ~1323.5 g/mol) with a D-His(benzyl) substitution at position 6. It is FDA-approved as a subdermal…
Kisspeptin is an endogenous neuropeptide encoded by the KISS1 gene that plays a critical role in regulating reproductive hormone secretion. It binds GPR54…
Full profiles: Histrelin, Kisspeptin.